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tPA dose in Stroke

Note:
Dosing Chart
Prepared as 1:1 dilution
For weight <41 kg, calculate dose 0.09 mg/kg
For weight >100 kg, Total dose = 90 mg
Lbs Kg 0.9 mg/kg 10% bolus 90% Infusion
90-94 41 37 mg / 37 ml 4 ml 33 ml
95-99 43 39 mg / 39 ml 4 ml 35 ml
100-104 45 41 mg / 41 ml 4 ml 37 ml
105-100 48 43 mg / 43 ml 4 ml 39 ml
110-114 50 45 mg / 45 ml 5 ml 40 ml
115-119 52 47 mg / 47 ml 5 ml 42 ml
120-124 55 50 mg / 50 ml 5 ml 45 ml
125-129 57 51 mg / 51 ml 5 ml 46 ml
130-134 59 53 mg / 53 ml 5 ml 48 ml
135-139 61 55 mg / 55 ml 6 ml 49 ml
140-144 64 58 mg / 58 ml 6 ml 52 ml
145-149 66 59 mg / 59 ml 6 ml 53 ml
150-154 68 61 mg / 61 ml 6 ml 55 ml
155-159 70 63 mg / 63 ml 6 ml 57 ml
160-164 73 66 mg / 66 ml 7 ml 59 ml
165-169 75 68 mg / 68 ml 7 ml 61 ml
170-174 77 69 mg / 69 ml 7 ml 62 ml
175-179 80 72 mg / 72 ml 7 ml 65 ml
180-184 82 74 mg / 74 ml 7 ml 67 ml
185-189 84 76 mg / 76 ml 8 ml 68 ml
190-194 86 77 mg / 77 ml 8 ml 69 ml
195-199 89 80 mg / 80 ml 8 ml 72 ml
200-204 91 82 mg / 82 ml 8 ml 74 ml
205-209 93 84 mg / 85 ml 8 ml 76 ml
210-214 95 86 mg / 86 ml 9 ml 77 ml
215-219 98 88 mg / 88 ml 9 ml 79 ml
220-224 100 90 mg / 90 ml 9 ml 81 ml
Lbs Kg 0.9 mg/kg 10% bolus 90% Infusion


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