overactivity
(acute salt
poisoning)
tubular disease
insipidus
intravascular space
replenishment)
& diuretics
Hypernatremia
| Cause | Renal Losses | Extrarenal losses |
Adrenocortical overactivity (acute salt poisoning) |
|
| Diuretics, tubular disease |
Diabetes insipidus |
|||
| Volume Status |
|
normal or |
|
|
| Total Body Sodium |
|
normal |
|
|
| Urine Na (mEq/l) | >20 | variable | <10 | >20 |
| Urine osmolality | normal or |
normal or |
|
normal or |
| Treatment (after intravascular space replenishment) |
hypotonic saline | H2O replacement | hypotonic saline | H2O replacement & diuretics |