Metabolic Acidosis

Signs & Symptoms
Elevated anion gap MUDPILES Normal anion gap (hyperchloremic)

 

M Methanol

U Uremia

D Diabetic ketoacidosis (and AKA)

P Propylene Glycol & Paraldehyde

I Iron & INH

L Lactic acidosis

E Ethylene glycol

S Salicylates & strychnine

Gastrointestinal bicarbonate loss

  • Diarrhea, small bowel drainage

  • Anion exchange resins

  • Ureterosigmoidostomy

Renal

  • RTA carbonic anhydrase inhibitors

  • Tubulointerstitial diseases

Miscellaneous

  • Hyperparathyroidism

  • Hyperalimentation (acidic amino acids)

  • Hypoaldosteronism